You should not use Xeljanz if you have a serious infection. Seek emergency medical help if you have sudden shortness of breath, chest pain spreading to your neck or arms, nausea, severe dizziness, a cold sweat, weakness on one side of your body, slurred speech, or pain, redness, or swelling in an arm or leg. Also tell your doctor if you've ever had diverticulitis, an ulcer in your stomach or intestines, cancer, a kidney transplant, heart problems, or a history of smoking, heart attack, stroke, or blood clots.Ĭall your doctor right away if you have a fever, night sweats, constant tiredness, weight loss, stomach pain, diarrhea or changes in bowel habits, trouble breathing, wheezing, a severe cough, or lumps in your neck, armpits, or groin. Tell your doctor if you have a weak immune system, diabetes, chronic lung disease, or an infection such as hepatitis, tuberculosis, shingles, or HIV. Taking Xeljanz may increase your risk of life-threatening medical problems including serious infections, a hole or tear in your digestive tract, a heart attack or stroke, blood clots, or cancer. Call your doctor if you have a fever, chills, aches, tiredness, cough, trouble breathing, skin sores, diarrhea, weight loss, or burning when you urinate. You may get infections more easily, even serious or fatal infections. Xeljanz is also used to treat polyarticular juvenile arthritis in adults and in children at least 2 years old.
Xeljanz is used to treat adults with active ankylosing spondylitis when 1 or more TNF blocker medicines have been used and did not work well or cannot be tolerated. Xeljanz is used to treat adults with moderate to severe ulcerative colitis in adults who cannot use certain other medications, or after other treatments have failed. Tofacitinib is sometimes given in combination with methotrexate or other arthritis medicines. Xeljanz is used to treat moderate to severe rheumatoid arthritis or active psoriatic arthritis in adults who have tried methotrexate or other medications without successful treatment of symptoms. Xeljanz ( tofacitinib) blocks the activity of certain enzymes in the body that affect immune system function. Medically reviewed by Judith Stewart, BPharm.
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